Publikacje

  1. Scott E; Archer Goode E; Garnham R; Hodgson K; Orozco-Moreno M; Turner H; Livermore K; Putri Nangkana K; Frame FM; Bermudez A; Jose Garcia Marques F; McClurg, UL; Wilson L; Thomas H; Buskin A; Hepburn A; Duxfield A; Bastian K; Pye H; Arredondo HM; Hysenaj G; Heavey S; Stopka-Farooqui U; Haider A; Freeman A; Singh S; Johnston EW; Punwani S; Knight B; McCullagh P; McGrath J; Crundwell M; Harries L; Heer R; Maitland NJ; Whitaker H; Pitteri S; Troyer DA; Wang N; Elliott DJ; Drake RR; Munkley J (2023) ST6GAL1-mediated aberrant sialylation promotes prostate cancer progression. The Journal of Pathology doi:10.1002/path.6152
  2. Scott E, Hodgson K, Calle B, Turner H, Cheung K, Bermudez A, Marques FJG, Pye HJ, Yo E, Islam K, Oo HZ, McClurg UL, Wilson L, Thomas H, Frame FM, Bastian KR, Arredondo HM, Kelly L, Tolson A, Mellor E, Hysenaj G, Goode EA, Livermore KE, Garnham R, Duxfield A, Knight B, McCullagh P, McGrath J, Crundwell M, Harries L, Bogdan D, Westaby D, Fowler G, Flohr P, Yuan W, Oakley F, Maitland N, Sharp A, de Bono J, Heer R, Guerrero RH, Daugaard M, Leivo J, Whitaker H, Pitteri S, Elliott DJ, Wang N, Schumann B, Munkley J. (2023) Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth. Oncogene 42(12), 926-937. doi:10.1038/s41388-023-02604-x
  3. Zhang J, Hu Z, Chung HH, Tian Y, Lau KW, Ser Z, Lim YT, Sobota RM, Leong HF, Chen BJ, Yeo CJ, Tan SYH, Kang J, Tan DEK, Sou IF, McClurg UL, Lakshmanan M, Vaiyapuri TS, Raju A, Wong ESM, Tergaonkar V, Rajarethinam R, Pathak E, Tam WL, Tan EY, Tee WW (2023). Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis. Nature communications, 14(1), 2439. doi:10.1038/s41467-023-38132-1
  1. Sou IF, Hamer G, Tee W-W, Vader G, McClurg UL (2022) Cancer and meiotic gene expression – two sides of the same coin? Invited book chapter: Chapter 11 in Meiosis in Development and Disease edited by Francesca Cole as art of Current Topics in Developmental Biology book series
  1. Sandhu S, Salmon LJ, Hunter JE, Wilson CL, Perkins ND, Hunter N, Davies OR, McClurg UL (2021) Centrosome dysfunction associated with somatic expression of the synaptonemal complex protein TEX12. Communications Biology 4:1371

  2. Sou IF, Pryce RM, Tee W-W, McClurg UL (2021) Meiosis initiation – a complex story of two sexes in all creatures great and small. Invited review, Biochem J 478 (20): 3791–3805.

  1. Prendergast L, McClurg UL, Hristova R, Hernandez Lopez I, Greener S, Rico D, Higgins JM, Gospodinov A, Papamichos-Chronakis M (2020) INO80 promotes resolution of R-loops to maintain cancer cell proliferation. Nature Communications 11, 4534 – Selected as Editors Highlight by Anne Mirabella

  2. Ndeh D, Baslé A, Strahl H, Yates EA, McClurg UL, Henrissat B, Terrapon N, Cartmell A (2020) Metabolism of multiple glycosaminoglycans by Bacteroides thetaiotaomicron is orchestrated by a versatile core genetic locus. Nature Communications 11(1), 646.

  1. McClurg UL, McCracken SR, Butler L, Riabowol KT, Binda O. (2018) Ex vivo culture and lentiviral transduction of Benign Prostatic Hyperplasia (BPH) samples. Bio Protoc. 2018, 8(21): pii: e3075.

  2. McClurg UL, Chit NCTH, Azizyan A, Edwards J, Nabbi A, Riabowol KT, Nakjang S, McCracken SR, Robson CN (2018) Molecular mechanism of the TP53-MDM2-AR-AKT signalling network regulation by USP12. Oncogene 2018, 37(34):4679-4691.

  3. McClurg UL, Azizyan M, Dransfield DT, Namdev N, Chit NCTH, Nakjang S, Robson CN (2018) The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46 to control prostate cancer growth and survival. Oncotarget 2018, 18;9, (38):24992-25007.

  4. McClurg UL, Nabbi A, Korolchuk S, McCracken SRC, Heer R, Wilson L, Butler LM, Irving-Hooper BK, Padeux R, Robson CN, Riabowol KT, Binda O (2018) Ex vivo tissue model system identifies ING3 as an oncoprotein. British Journal of cancer 2018, 118(5):713-726.

  1. Munkley J, McClurg UL, Livermore KE, Knight B, Mccullagh P, Mcgrath J, Crundwell M, Harries LW, Leung HY, Mills IG, Robson CN, Rajan P, Elliott DJ (2017) The cancer-associated cell migration protein TSPAN1 is under direct control of androgens and is upregulated in prostate cancer cells. Scientific Reports 2017, 7(1) 5249-56.

  2. Nabbi A, McClurg UL, Thalappilly S, Almami A, Mobahat M, Bismar TA, Binda O, Riabowol K (2017) ING3 promotes prostate cancer growth by activating the androgen receptor BMC Medicine 2017, 15(1):103-125.

  3. McClurg UL, Cork DMW, Darby S, Ryan-Munden CA, Mendes-Cortes L, Gaughan L, Robson CN (2017) Identification of a novel K311 ubiquitination site critical for androgen receptor transcriptional activity. Nucleic Acids Research 2017, 45(4): 1793-1804.

  1. Logan IR, McClurg UL, Jones DL, O’Neill DJ, Shaheen FS, Lunec J, Gaughan L, Robson CN (2016) Nutlin-3 Inhibits androgen receptor-driven c-FLIP expression, resulting in apoptosis of prostate cancer cells. Oncotarget 2016, 7(46) 74724-33.

  2. Kim S, Natesan S, Cornilescu G, Carlson S, Tonelli M, McClurg UL, Binda O, Robson CN, Markley JL, Balaz S, Glass KC (2016) Mechanism of histone H3K4me3 recognition by the plant homeodomain of inhibitor of growth 3. J Biol Chem 2016, 291(35): 18326-41.

  1. McClurg UL, Harle VJ, Nabbi A, Batalha-Pereira A, Walker S, Coffey K, Gaughan L, McCracken SRC, Robson CN (2015) Ubiquitin-Specific Protease 12 interacting partners Uaf-1 and WDR20 are potential therapeutic targets in prostate cancer. Oncotarget 2015, 6(15): 37724-37736.

  2. Munkley J, Livermore K, McClurg UL, Kalna G, Knight B, McCullagh P, McGrath J, Crundwell M, Leung H, Robson CN, Harries L, Rajan P, Elliott D (2015) The PI3K regulatory subunit gene PIK3R1 is under direct control of androgens and repressed in prostate cancer cells. Oncoscience 2015, 2(9): 755-764.

  3. McClurg UL, Robson CN (2015) Deubiquitinating enzymes as oncotargets, Invited review, Oncotarget 2015, 6(12): 9657-9668.

  4. McClurg UL, King HO, Danjo K, Scott G, Robinson PA, Crabtree JE (2015) Epithelial cell ADAM17 activation by Helicobacter pylori: role of ADAM17 C-terminus and Threonine-735 phosphorylation. Microbes and Infection 2015, 17(3): 205-14.

  1. McClurg UL, Summerscales EE, Harle VJ, Gaughan L, Robson CN (2014) Deubiquitinating enzyme USP12 regulates the interaction between the androgen receptor and the AKT pathway. Oncotarget 2014, 5(16): 7081-92.

  2. Burska UL, Fletcher J (2014) Two plasmid encoded genes of Enteropathogenic E. coli strain K798 promote invasion and survival within HEp-2 cells. APMIS (Acta pathologica, microbiologica et immunologica Scandinavica) 2014, 122(10): 922-30.

  1. Burska UL, Harle VJ, Coffey K, Darby S, Ramsey H, O’Neill D, Logan IR, Gaughan L, Robson CN (2013) Deubiquitinating enzyme USP12 is a novel co-activator of the androgen receptor. J Biol Chem 2013, 288 (45): 32641-650.