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Publications
Some of our publications
- Al-Warhi T, Sabt A, Korycka-Machala M, Kassem AF, Shaldam MA, Ibrahim HAA, Kawka M, Dziadek B, Kuzioła M, Eldehna WM, Dziadek J. Benzenesulfonohydrazide-tethered non-fused and fused heterocycles as potential anti-mycobacterial agents targeting enoyl acyl carrier protein reductase (InhA) with antibiofilm activity. RSC Adv. 2024 Sep 23;14(41):30165-30179.
- Sabt A, Abdulla MH, Ebaid MS, Pawełczyk J, Abd El Salam HA, Son NT, Ha NX, Vaali Mohammed MA, Traiki T, Elsawi AE, Dziadek B, Dziadek J, Eldehna WM. Identification of 2-(N-aryl-1,2,3-triazol-4-yl) quinoline derivatives as antitubercular agents endowed with InhA inhibitory activity. Front Chem. 2024 Aug 7;12:1424017.
- Sabt A, Khaleel EF, Shaldam MA, Ebaid MS, Mustafa Badi R, Allayeh AK, Eldehna WM, Dziadek J. Discovery of new quinoline derivatives bearing 1-aryl-1,2,3-triazole motif as influenza H1N1 virus neuraminidase inhibitors. Bioorg Chem. 2024 Oct;151:107703.
- Płocińska R, Struś K, Korycka-Machała M, Płociński P, Kuzioła M, Żaczek A, Słomka M, Dziadek J. MnoSR removal in Mycobacterium smegmatis triggers broad transcriptional response to 1,3-propanediol and glucose as sole carbon sources. Front Cell Infect Microbiol. 2024 Jul 24;14:1427829.
- Khaleel EF, Sabt A, Korycka-Machala M, Badi RM, Son NT, Ha NX, Hamissa MF, Elsawi AE, Elkaeed EB, Dziadek B, Eldehna WM, Dziadek J. Identification of new anti-mycobacterial agents based on quinoline-isatin hybrids targeting enoyl acyl carrier protein reductase (InhA). Bioorg Chem. 2024 Mar;144:107138.
- Błaszczyk E, Płociński P, Lechowicz E, Brzostek A, Dziadek B, Korycka-Machała M, Słomka M, Dziadek J. Depletion of tRNA CCA-adding enzyme in Mycobacterium tuberculosis leads to polyadenylation of transcripts and precursor tRNAs. Sci Rep. 2023 Nov 24;13(1):20717.
- Kawka M, Płocińska R, Płociński P, Pawełczyk J, Słomka M, Gatkowska J, Dzitko K, Dziadek B, Dziadek J. The functional response of human monocyte-derived macrophages to serum amyloid A and Mycobacterium tuberculosis infection. Front Immunol. 2023 Sep 15;14:1238132.
- Płocińska R, Wasik K, Płociński P, Lechowicz E, Antczak M, Błaszczyk E, Dziadek B, Słomka M, Rumijowska-Galewicz A, Dziadek J. The orphan response regulator Rv3143 modulates the activity of the NADH dehydrogenase complex (Nuo) in Mycobacterium tuberculosis via protein-protein interactions. Front Cell Infect Microbiol. 2022 Jun 28;12:909507.
- Pawełczyk J, Brzostek A, Minias A, Płociński P, Rumijowska-Galewicz A, Strapagiel D, Zakrzewska-Czerwińska J, Dziadek J. Cholesterol-dependent transcriptome remodeling reveals new insight into the contribution of cholesterol to Mycobacterium tuberculosis pathogenesis. Sci Rep. 2021 Jun 11;11(1):12396.
- Minias A, Gąsior F, Brzostek A, Jagielski T, Dziadek J. Cobalamin is present in cells of non-tuberculous mycobacteria, but not in Mycobacterium tuberculosis. Sci Rep. 2021 Jun 10;11(1):12267.
- Brzostek A, Płociński P, Minias A, Ciszewska A, Gąsior F, Pawełczyk J, Dziadek B, Słomka M, Dziadek J. Dissecting the RecA-(In)dependent response to mitomycin C in Mycobacterium tuberculosis using transcriptional profiling and proteomics analyses. Cells. 2021 May 11;10(5):1168.
- Brissett NC, Zabrady K, Płociński P, Bianchi J, Korycka-Machała M, Brzostek A, Dziadek J, Doherty AJ. Molecular basis for DNA repair synthesis on short gaps by mycobacterial primase-polymerase C. Nat Commun. 2020 Aug 21;11(1):4196. doi: 10.1038/s41467-020-18012-8.
- Płociński P, Macios M, Houghton J, Niemiec E, Płocińska R, Brzostek A, Słomka M, Dziadek J, Young D, Dziembowski A. Proteomic and transcriptomic experiments reveal an essential role of RNA degradosome complexes in shaping the transcriptome of Mycobacterium tuberculosis. Nucleic Acids Res. 2019 Apr 8. pii: gkz251. doi: 10.1093/nar/gkz251.
- Korycka-Machała M, Viljoen A, Pawełczyk J, Borówka P, Dziadek B, Gobis K, Brzostek A, Kawka M, Blaise M, Strapagiel D, Kremer L, Dziadek J. 1H-benzo[d]imidazole derivatives affect MmpL3 in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2019 Jul 22. pii: AAC.00441-19.
- Antczak M, Płocińska R, Płociński P, Rumijowska-Galewicz A, Żaczek A, Strapagiel D, Dziadek J. The NnaR orphan response regulator is essential for the utilization of nitrate and nitrite as sole nitrogen sources in mycobacteria. Sci Rep. 2018 Dec 3;8(1):17552.
- Jagielski T, Bakuła Z, Brzostek A, Minias A, Stachowiak R, Kalita J, Napiórkowska A, Augustynowicz-Kopeć E, Żaczek A, Vasiliauskiene E, Bielecki J, Dziadek J. Characterization of mutations conferring resistance to rifampicin in Mycobacterium tuberculosis clinical strains. Antimicrob Agents Chemother. 2018 Jul 30. pii: AAC.01093-18. doi: 10.1128/AAC.01093-18.
- Płociński P, Brissett NC, Bianchi J, Brzostek A, Korycka-Machała M, Dziembowski A, Dziadek J, Doherty AJ. DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria. Nat Commun. 2017 Nov 1;8(1):1251.