Epigenetics

The research conducted in our laboratory focuses on studying the epigenetic mechanisms that play a role in regulating genes associated with the differentiation of Th17 cells. Th17 cells are a specific subset of T helper lymphocytes that produce interleukins 17A and 17F. These cells have been implicated in initiating detrimental immune responses that lead to tissue destruction in autoimmune diseases. Our research aims to unravel the precise molecular mechanisms underlying the epigenetic changes during Th17 cell differentiation.

By gaining a deeper understanding of these mechanisms, we anticipate that we can eventually intervene directly in these processes. For instance, we hope to modulate the negative impact of Th17 lymphocytes in autoimmune diseases by targeting the specific epigenetic changes involved.