Research profile

Genome-wide bioinformatics analyses based on the presence and distribution of microsatellite sequences in the analyzed genomes. In particular, the study of bacterial genomes correlating the relationship of positions in the genomes of trinucleotide motifs (TRS) and the size of sequence fragments between them, allowing to demonstrate the high differentiation power of closely related organisms. For example, in the case of selected genomes of M. tuberculosis, where the similarity of the genomes is very high (>90%), the methodology allowed to separate groups of genomes from two different phylogenetic lines.