Current research

Dr Izabela Papiewska-Pająk is currently engaged in the following:

• Characterization of the content of extracellular vesicles secreted by colorectal cancer cells with different metastatic potentials and induced by endogenous (transcription factor Snail) or exogenous (hypoxic conditions) factors.
• Studying the effect of extracellular vesicles secreted under different conditions by colon cancer cells on elements of the pre-metastatic niche in vitro and in vivo studies.
• Investigating the function of microvesicles secreted by platelets during colorectal cancer progression, in vitro and in vivo studies.

Dr Jakub Kryczka is currently engaged in the following:

• Research on the phenomenon of chemo-resistance of cancer cells and its impact on their migratory abilities
• Developing algorithms to support decision-making and anti-cancer therapies based on bioinformatic analysis of big data sets.

Dr Hassan Kassassir is currently engaged in the following:

• Identifying the role of platelet microvesicles as carriers of signaling molecules transported to cancer cells
• Identifying platelet interactions with tumor cells in the context of colorectal cancer metastasis
• Searching for new methods in immunotherapy using platelet microvesicles as carriers of antibodies
• Investigating the vascular endothelium as a barrier to tumor cells in large datasets.