Instytut Biologii Medycznej PAN

Projects > Current Projects > EU-OPENSCREEN

6 December 2018

POL-OPENSCREEN Project (Polish Infrastructure of Screening Platform for Biological Chemistry), a mutual undertaking of Polish Consortium operating under the same name, is part of EU-OPENSCREEN Consortium (www.eu-openscreen.eu). The objective of EU-OPENSCREEN Project is to ensure that Europe and countries participating in the project take leading positions in the area of biological and medical studies and to stimulate industrial studies as well as commercial use of the European potential in seeking and introducing new bioactive substances for medicine, agriculture, cosmetology and other branches; also to get an access to results of research studies and development work.
The project is aimed at preparing a database, providing the structure and next use the pan-European infrastructure enabling to create collections of chemical compounds, high-capacity screening studies, chemical synthesis and optimization methods of receiving compounds – candidates for new medicines, also bioprofiling and in vivo tests of these compounds. It is assumed that the database created will be open and accessible to all interested research institutions, universities as well as pharmaceutical industry on certain determined rules.

On 20 March 2018 the European Commission took a decision to give the EU-OPENSCREEN Consortium a status of the European research infrastructure consortium, European Research Infrastructure Consortium (ERIC). Following the decision of Ministry of Science and Higher Education, Poland has become one of EU-OPENSCREEN ERIC founding member countries.

Objectives and tasks of Polish partnership are convergent with those represented by international consortia, considering competence of particular units and Polish specific character and needs. Two complementary undertakings are currently under the way: the National Library of Chemical Compounds (NLCC) to operate at the Institute of Biological Medicine (IBM) PAN and consolidation and strengthening of the existing national screening infrastructure to intensify biological screening and search for new bioactive chemical compounds.

Now POL-OPENSCREEN consortium is made up of 7 institutions and research centres involved in life sciences, seeking new biologically active compounds and doing tests of medicines (given in alphabetical order): Centre of Molecular and Macromolecular Studies (CBMiM) PAN in Łódź, Institute of Biochemistry and Biophysics (IBB) PAN in Warsaw, Institute of Medical Biology (IBM) PAN (POL-OPENSCREEN consortium coordinator), Institute of Biotechnology and Antibiotics (IBA) in Warsaw, Institute of Bioorganic Chemistry (ICHB) PAN in Poznań, Pharmaceutical Research Institute (IF) in Warsaw and Institute of Pharmacology (IF) PAN in Kraków. POL-OPENSCREEN Consortium is open to any new members and partners.

Following the evaluation carried out by an international team of experts, three Polish institutions, members of POL-OPENSCREEN consortium, i.e.: Institute of Biological Medicine PAN, Institute of Biochemistry and Biophysics PAN and Institute of Bioorganic Chemistry PAN, acquired a status of “partner sites” of the European EU-OPENSCREEN ERIC Consortium. On 24 October 2018 IBM PAN, a coordinator of the consortium,  was given the decision of Ministry of Science and Higher Education regarding the application filed in the name of POL-OPENSCREN consortium for 39 million Pln subsidy to finance the participation of three distinguished institutions in the European consortium. The funds will be channelled into the National Library of Chemical Compounds and into the extension of screening infrastructure.

It should be emphasized that the National Library of Chemical Compounds will be the first such undertaking in the country.  It is also worth mentioning that the research infrastructure planned will not only have a transregional but also an international reach.